How Chitosan Can Help With Wound Healing

In the last decade, biopolymers have been of growing interest to scientists for their non-toxic, biocompatible, biodegradable and non-allergenic properties. Such products have been on the market since the early 1990s, with excellent results. As chitosan manufacturers with over 20 years of experience, we provide our customers with high-quality, pure chitosan in a number of formats, including chitosan powder, with multiple applications, including wound healing.

how chitosan can assist with Wound healing

Chitosan is a biocompatible biopolymer with bacteriostatic, fungistatic, film-forming properties that are crucial to wound treatment. Chitosan's reparative nature allows it to restore or replace damaged tissue, while promoting healing and producing less scarring.

Schematic representation of the benefits of chitosan wound dressing, from "Chitosan and Alginate Wound Dressings: A Short Review" Trends in Biomaterials and Artificial Organs, 18, by Paul, Willi & Sharma, Chandra P. (2004).

Chitosan wound healing properties:

• Hemostatic
• Bio-adhesive
• Antibacterial
• Antifungal
• Anti-viral
• Anti-inflammatory
• Protects wounds from bacterial and microbial infection
• Promotes cellular and tissue regeneration
• Restores or replaces damages tissue
• Produces less scarring

Thanks to chitosan's film-forming nature, it creates a thin film over the skin, covering its surface without cracking. This provides an extra protective layer that locks in moisture while keeping out bacteria and microbes. As chitosan is antibacterial, antifungal and analgesic, it inhibits further bacterial and fungal growth by promoting structural changes in the membrane-wall complex, causing impaired surface cell structure and bacterial death.

Aside for protecting wounds, chitosan films are permeable to air. They facilitate cellular regeneration, dramatically speeding up wound healing. Chitosan's ability to film-form also contributes to effectively treating eczema and acne, protecting the skin from future breakouts. It reduces infection and has antipruritic (anti-itch) and anti-inflammatory properties, preventing scarring and delivering a soothing effect.

Chitosan and Drug administration

Chitosan's ability to deliver drugs and other therapeutic compounds has been well documented and this also applies to wound healing. Drug delivery systems based on polysaccharides have revolutionized medical treatments due to their efficient and appropriate drug delivery. Chitosan facilitates the transport of nutrients and oxygen and, as it has no antigenic properties, it has excellent biocompatibility. Chitosan-based devices can combine drug delivery with wound healing, making them exceptionally efficient.

Chitosan Wound healing formats

Chitosan-based hydrogels can be used for drug delivery in wound dressings, while films and fibers can be developed for tissue engineering, wound care, and water-resistant adhesives.

Antimicrobial action, film-forming ability and wound-healing properties make chitosan suitable for the development of a wound dressings, including ocular bandage lenses for traumatic injuries. As ocular wounds and eye injuries are exceptionally sensitive, chitosan's biocompatibility, non-allergenic and non-toxic nature proves exceptionally useful.

 

ChitoCare Medical devices

Primex chitosan products in this category include ChitoCare Medical devices, that have been developed specifically to treat contaminated, old, new or chronic wounds, burns and scars in both humans and animals.

ChitoCare Medical Gel can be used in wet wound dressing, while the gel's drying effect is advantageous in wet eczema treatment, avoiding wound covering.

Both ChitoCare Medical Gel and Spray are useful under wound dressings and in field treatment, respectively, of animals. They decrease itching, enhance hyper-granulation, promote healing, and reduce self-mutilation at a later stage.

 

CHITOSAN CAN BE DEVELOPED INTO:

• Bandages
• Membranes
• Nanogels
• Films
• Nanofibers
• Hydrogels
• Nanoparticles
• Beads
• Nonwovens
• Composites
• Sponges

For more information, please visit our Products page . If you would like to buy chitosan or are looking for a state-of-the-art chitosan factory to help serve your needs, feel free to contact us so that we can better assist you and answer any questions.