How Chitosan Is Effective for Weight Management

Chitosan was first discovered to have beneficial properties back in the 1980s. It has primarily been used in the nutraceutical industry and has been developed into functional foods, dietary supplements and herbal or natural products.

Chitosan has proven effective as a weight loss supplement. As it is a naturally fibrous biopolymer, it can actively absorb oils, fats and lipids – up to eight times its weight! This makes it an excellent option for treating obesity, cholesterol, and other related diseases and conditions.  

Chitosan has been approved by the US Food and Drug Administration as a safe food additive, dietary fibre, and functional ingredient for consumer use.  

Chitosan properties and bioactivities: 

  • Antimicrobial  
  • Antioxidant 
  • Fat-binding  
  • Prebiotic 
  • Anti-inflammatory 
  • Anti-carcinogenic 
  • Antiulcer  

Weight loss and management 

Obesity is a well-established risk factor for cardiovascular disease, diabetes, hyperlipidaemia, hypertension, osteoarthritis, and strokes. Considering current scientific knowledge and population needs, it appears tactical to provide weight management solutions to tackle the obesity epidemic while promoting calorie restriction to enhance overall wellness. 

Chitosan has nutraceutical properties, including antibacterial, anti-inflammatory, antioxidant, anti-carcinogenic and antiulcer bioactivities, including its application as a dietary fibre with fat-binding qualities. Chitosan and its derivatives have been shown to lower cholesterol by blocking the absorption of dietary fat and cholesterols. They can also facilitate weight low and body fat loss in humans, subsequently lowering systolic and diastolic blood pressure. Chitosan is also a valuable prebiotic, promoting colonic conditions. 

Primex ChitoClear® chitosan 

Chitosan is a versatile, natural biopolymer that has found a variety of applications in all areas of the food sciences. Chitosan has many intrinsic nutritional values, such as antioxidant properties and health-promoting bioactivities against many chronic diseases, including hypercholesterolemia, hypertension, inflammation, immune diseases, etc.  

In addition, chitosan has excellent emulsifying properties and is used to stabilize various oil-in-water emulsions to avoid the use of synthetic surfactants. The intrinsic properties vary with the molecular weight (MW) and degree of deacetylation (DDA), which are the most important characteristics of chitosan. Indeed, chitosan can be used at low concentration in the food industry for its various functional properties, but its main application has been in the dietary supplement market. 

A recent study assessed the selective fat-binding capacity of ChitoClear® chitosan to different fat types, monitoring fatty acid absorption, neutral sterol and bile acid excretion in guinea pigs, a suitable animal model due to its similarities with human lipid metabolism. This is significant, as different fat types have different metabolism in animals and humans. The results show that ChitoClear® chitosan selectively reduces fat absorption and has a higher affinity to binding fatty acids with higher polarity. 

Clinically proven weight loss by Primex Liposan Ultra 

Primex products in this category include Liposan Ultra, that has been formulated into LipoSan & Vitamin C, Liposan Hair, Skin & Nails, and Liposan Micro. The active ingredient is Primex ChitoClear® chitosan, a unique and proprietary dietary fiber formulation. 

Liposan Ultra 

Liposan Ultra has a higher density and solubility that chitosan itself. By mixing Vitamin C with our proven Liposan Ultra, increased effectiveness of each capsule has been achieved. In addition to the well-known benefits of Vitamin C, this formulation also reduces the time it takes Liposan Ultra to dissolve. Within three minutes of working in the stomach, over 90% of the Liposan Ultra is already working on neutralizing meal-derived fat. 

Liposan Hair Skin & Nails 

Liposan Hair Skin & Nails is a natural marine formula that perfectly balances with fish cartilage extract to create the ultimate hair, skin and nails product. This chitosan-based product contains Icelandic LipoSan fibres that are supplemented with hydrolysed fish collagen Type ll, known for its antioxidant properties. It is rich in algae, that stimulates collagen renewal and possesses nourishing, anti-ageing, and moisturizing properties. This proprietary blend also contains silica, a mineral compound of lava, famously found in Iceland's Blue Lagoon and known for strengthening the skin's barrier function. It also incorporates Vitamin C, zinc, selenium, magnesium, and calcium, that help protect cells from oxidative stress. LipoSan Hair, Skin & Nails is available as a retail finished product under the brand name ChitoCare Beauty Hair, Skin & Nails

Liposan Micro 

Finally, Liposan Micro is a Primex patented formulation. It is micro-coated to remove any taste and can be added to food in the form of micro-granulated dust.